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When public refer to today’s medicine, precision plays one of the most significant roles and people’s lives are literally dependent on it. Likewise, any researches pertaining to medicine are necessary to comply with the highest standards. The issue today is that any results of researches can be posted online and used as a reference without being thoroughly checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and tried to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The main principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to validate publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with corresponding scores above 1

Researchers identify genomic regions in DNA with hypermethylation, abundant MSRE sites, and low methylation levels that can be amplified and detected using MSRE-PCR analysis in diverse types of tumor DNA and normal tissue. oncotarget breakthrough DNMT3 is an enzyme from a group of DNA methlytransferases, which modify DNA in order to regulate gene expression and activity. DNMT3 is an enzyme from a group of DNA methlytransferases, which modify DNA in order to regulate gene expression and activity. A pair of U.S. researchers from Johns Hopkins University in Baltimore, Maryland, and from Genmab—an international biotech company in Princeton, New Jersey—collaborated in a study to demonstrate: “Selective amplification of hypermethylated DNA from diverse tumor types via MSRE-PCR.” This study was published as the cover paper of journal Volume 11, Issue #47 in Oncotarget. oncotarget Methylation Errors Methylation is an important process in multiple functions in human DNA, including gene regu

When people mention contemporary medicine, accuracy plays one of the most crucial roles and human lives are directly dependent on it. Hereby, any researches related to medicine are necessary to meet the top standards. The challenge today is that any conclusions of researches can be shared online and used as a reference without being thoroughly verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and attempted to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with corresponding scores above 100 as well as re

In a case presentation paper, Encyclopedic Tumor Analysis guided researchers in identifying HER2 overexpression in a patient with distal common bile duct carcinoma and in personalizing his treatment regimen. Oncotarget Youtube The Trending with Impact series highlights publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here and at Oncotarget.com. — Researchers from multiple highly-regarded institutions located in India and from the Medical College of Wisconsin in the United states wrote a paper on the case presentation: “Liquid biopsy and multi-analyte testing guided treatment of HER2 positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy”—published in Oncotarget. Oncotarget’s Out of people living with periampullary adenocarcinoma, 12% of patients show a mixed

When public mention modern medicine, accuracy plays one of the most crucial roles and human lives are literally dependent on it. Likewise, any researches pertaining to medicine are required to comply with the highest standards. The issue nowadays is that any results of researches can be published online and used as a reference without being properly checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and attempted to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality indicator. That assists both readers and authors to validate publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a full publications list with respective scores higher than 100 as we

When general population mention modern medicine, precision plays one of the most important roles and people’s lives are literally dependent on it. Hereby, any researches pertaining to medicine are necessary to comply with the highest standards. The challenge today is that any outcomes of researches can be posted online and used as a reference without being precisely checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and tried to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality measure. That assists both readers and authors to quality-check publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a complete publications list with corresponding scores above 100

This review compiles splice variations in HER2 breast cancer, specifically in the context of the tumor environment, and co-expression of variants. The study also provides an up-to-date (as of Nov. 2020) account of HER2 and HER2 variant patterns of resistance to anti-HER2 therapies and other interventions. Oncotarget’s The Trending with Impact series highlights Oncotarget publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here, and at Oncotarget.com. — Listen to an audio version of this article According to Cancer Research UK, breast cancer occurs in one in every eight women within their lifetime and is the second highest cause of cancer related deaths in the UK. Breast cancer is a blanketed term for a wide variety of tumors that occur in the mammary glands. In over 20% of breast cancers, the human epiderma

When general population speak of contemporary medicine, precision plays one of the most significant roles and human lives are directly dependent on it. Likewise, any researches related to medicine are required to meet the highest standards. The issue nowadays is that any conclusions of researches can be posted online and used as a reference without being adequately checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and tried to develop an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a complete publications list with respective scores abo

“The current study is the first of its kind, wherein comprehensive transcriptome analysis using RNA-Seq was performed in Notch2 depleted B-cell lymphoma cells.” Chicago hospital Malignant effusion cytology: microscopic image of diffuse large B-cell lymphoma, a type of non Hodgkin lymphoma. Malignant effusion cytology: microscopic image of diffuse large B-cell lymphoma, a type of non Hodgkin lymphoma. The Trending with Impact series highlights Oncotarget publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here, and at Oncotarget.com. Los Angeles hospital Splenic marginal zone lymphoma (SMZL) is a rare subtype of non-Hodgkin lymphoma that comprises approximately 10% of all lymphoma cases. Marginal zone lymphoma (MZL) originates from B memory lymphocytes (B-cells) in the marginal zone of secondary lymphoid foll

When people refer to today’s medicine, accuracy plays one of the most crucial roles and people’s lives are literally dependent on it. Likewise, any researches related to medicine are required to meet the highest standards. The problem today is that any recommendations of researches can be shared online and used as a reference without being precisely verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this challenge and tried to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The major principle of this journal is based on Altmetric scores that are used as a quality indicator. That allows both readers and authors to verify publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a full publications list with corresponding scores above 100 as well as

When people refer to today’s medicine, accuracy plays one of the most significant roles and people’s lives are directly dependent on it. Hereby, any researches pertaining to medicine are required to meet the highest standards. The challenge today is that any outcomes of researches can be posted online and used as a reference without being adequately verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and tried to generate an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality indicator. That allows both readers and authors to validate publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with respective scores above 100 as well as

The coronavirus pandemic put the practice of hand-washing front and center. This proven method of killing germs gave the general public the key tool it needed to lower infection rates. With this in mind, Oncotarget, www.oncotarget.com, published by Impact Journals wants to remind the public just how important it is to wash their hands regularly, especially during the pandemic. Please check a special issue related to COVID-19 ( https://www.aging-us.com/special-collections-archive/covid-19 ) in Aging journal, which is also published by Impact Journals. The history of hand-washing doesn’t date as far back as some may expect, but the effort is rooted in something as significant as stemming the coronavirus outbreak. Read on to discover how a Hungarian physician was able to reduce the mortality rates of new mothers down to zero after being faced with a perplexing problem at Vienna hospital. Hand-washing is commonly accepted today as a practice intended to protect ourselves from the transmi

When public speak of contemporary medicine, precision plays one of the most important roles and people’s lives are literally dependent on it. Hence, any researches pertaining to medicine are required to meet the top standards. The problem nowadays is that any recommendations of researches can be posted online and used as a reference without being properly checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and decided to develop an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The key principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to validate publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with corresponding scores above 100 as

This in vitro study represents the first individual comparison of a tier one drug, encorafenib, and two other paradox breaker inhibitors in the treatment of colorectal cancer with BRAF mutations. Colorectal cancer, medical anatomical illustration Colorectal cancer, medical anatomical illustration The Trending with Impact series highlights publications attracting higher visibility among readers around the world online, in the news, and on social media beyond normal readership levels. Look for future science news and articles about the latest trending publications here. — Colorectal cancer (CRC) is a cancer beginning in the colon or the rectum. Among cancers that affect both men and women in the United States, CRC is the second leading cancer killer (likely due to a lack of screening for early detection). This statistic has propelled many scientists over the years to study the disease in order to develop better therapies and treatments. In previous studies, researchers have found tha

When people discuss modern medicine, accuracy plays one of the most significant roles and human lives are directly dependent on it. Hence, any researches related to medicine are necessary to meet the highest standards. The challenge nowadays is that any results of researches can be posted online and used as a reference without being adequately checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this issue and attempted to develop an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality measure. That allows both readers and authors to verify publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a complete publications list with corresponding scores above 100 as well as reports m

When public speak of contemporary medicine, precision plays one of the most crucial roles and human lives are literally dependent on it. Hereby, any researches related to medicine are necessary to comply with the highest standards. The problem nowadays is that any outcomes of researches can be shared online and used as a reference without being precisely verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this challenge and tried to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The main principle of this journal is based on Altmetric scores that are used as a quality indicator. That allows both readers and authors to verify publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with respective scores above 100 as well

Researchers find that the methylation of a newly identified region of the INS-IGF2 gene is responsible for IGF2 expression in breast cancer tumors and in breast cancer cells. Breast cancer core biopsy - ductal carcinoma in situ (DCIS) detected by screening mammography Breast cancer core biopsy – ductal carcinoma in situ (DCIS) detected by screening mammography Determined to learn more and find new methods to eradicate breast cancer, a team of researchers turned their sights on a mechanism that could be a key in novel therapies: the IGF2 gene. Based out of the United States’ California and Colorado, the researchers examined a particular gene in the DNA, located on Chromosome 11, and its functions in normal and breast cancer cells. IGF2 Expression in Breast Cancer The IGF2 gene is a growth factor that plays an important role in regulating stem cell activity and liver function in adults. This gene can be inhibited or stimulated by hormones, stress, nutrition, tumor suppressors, and o

When people discuss today’s medicine, accuracy plays one of the most crucial roles and human lives are literally dependent on it. Likewise, any researches related to medicine are necessary to comply with the highest standards. The challenge nowadays is that any results of researches can be posted online and used as a reference without being adequately checked and approved. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and tried to create an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been founded back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality measure. That allows both readers and authors to validate publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with corresponding scores above 100 as well as rep

Researchers from Germany starved breast cancer cells of amino acids, including methionine, and exploited their dependency on the amino acid transporter SLC6A14. 3D Illustration of a chain of amino acids 3D Illustration of a chain of amino acids Cancerous tumors are greedy invaders. In order to sustain their signature high rate of growth, proliferation, and to increase their metabolic capacity, tumor cells demand more nutrients from the body, such as glucose and amino acids. One way that tumor cells elevate this intake of nutrients is by increasing the expression of genes that encode amino acid transporters. This knowledge provided new potential therapeutic targets for the authors of the cover paper for Oncotarget’s Vol 11, Issue #48. “Targeting tumor metabolism has been explored as a strategy to inhibit tumor growth and proliferation due to the elevated metabolic requirements of cancer cells compared to their normal counterparts [1].” Researchers from Germany organized the study, “

When public speak of modern medicine, accuracy plays one of the most crucial roles and people’s lives are directly dependent on it. Hereby, any researches related to medicine are necessary to meet the top standards. The issue today is that any outcomes of researches can be shared online and used as a reference without being precisely verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget perfectly understood this problem and decided to come up with an alternative solution. That’s how a weekly oncology-focused research journal named “Oncotarget” has been established back in 2010. The main principle of this journal is related to Altmetric scores that are used as a quality indicator. That assists both readers and authors to verify publications with Altmetric Article Reports that provide “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a complete publications list with corresponding scores above 100 as well as rep