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Trending with Impact: MSRE-PCR Detects Hypermethylated DNA in Tumors

января 28, 2021

Researchers identify genomic regions in DNA with hypermethylation, abundant MSRE sites, and low methylation levels that can be amplified and detected using MSRE-PCR analysis in diverse types of tumor DNA and normal tissue. oncotarget breakthrough DNMT3 is an enzyme from a group of DNA methlytransferases, which modify DNA in order to regulate gene expression and activity. DNMT3 is an enzyme from a group of DNA methlytransferases, which modify DNA in order to regulate gene expression and activity. A pair of U.S. researchers from Johns Hopkins University in Baltimore, Maryland, and from Genmab—an international biotech company in Princeton, New Jersey—collaborated in a study to demonstrate: “Selective amplification of hypermethylated DNA from diverse tumor types via MSRE-PCR.” This study was published as the cover paper of journal Volume 11, Issue #47 in Oncotarget. oncotarget Methylation Errors Methylation is an important process in multiple functions in human DNA, including gene regu

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us clinics lists

января 27, 2021

When people mention contemporary medicine, accuracy plays one of the most crucial roles and human lives are directly dependent on it. Hereby, any researches related to medicine are necessary to meet the top standards. The challenge today is that any conclusions of researches can be shared online and used as a reference without being thoroughly verified and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and attempted to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The major principle of this journal is related to Altmetric scores that are used as a quality measure. That assists both readers and authors to verify publications with Altmetric Article Reports that create “real-time feedback containing data summary related to a particular publication. ” Oncotarget website demonstrates a full publications list with corresponding scores above 100 as well as re

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Trending with Impact: Exacta® Guides Treatment and Identifies HER2

января 26, 2021

In a case presentation paper, Encyclopedic Tumor Analysis guided researchers in identifying HER2 overexpression in a patient with distal common bile duct carcinoma and in personalizing his treatment regimen. Oncotarget Youtube The Trending with Impact series highlights publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here and at Oncotarget.com. — Researchers from multiple highly-regarded institutions located in India and from the Medical College of Wisconsin in the United states wrote a paper on the case presentation: “Liquid biopsy and multi-analyte testing guided treatment of HER2 positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy”—published in Oncotarget. Oncotarget’s Out of people living with periampullary adenocarcinoma, 12% of patients show a mixed

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us hospitals lists

января 26, 2021

When public mention modern medicine, accuracy plays one of the most crucial roles and human lives are literally dependent on it. Likewise, any researches pertaining to medicine are required to comply with the highest standards. The issue nowadays is that any results of researches can be published online and used as a reference without being properly checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this problem and attempted to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been established back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality indicator. That assists both readers and authors to validate publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website provides a full publications list with respective scores higher than 100 as we

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us hospitals lists

января 21, 2021

When general population mention modern medicine, precision plays one of the most important roles and people’s lives are literally dependent on it. Hereby, any researches pertaining to medicine are necessary to comply with the highest standards. The challenge today is that any outcomes of researches can be posted online and used as a reference without being precisely checked and validated. Mikhail (Misha) Blagosklonny of Oncotarget clearly understood this issue and tried to create an alternative solution. That’s how a weekly oncology-focused research journal called “Oncotarget” has been founded back in 2010. The key principle of this journal is based on Altmetric scores that are used as a quality measure. That assists both readers and authors to quality-check publications with Altmetric Article Reports that generate “real-time feedback containing data summary related to a particular publication. ” Oncotarget website has a complete publications list with corresponding scores above 100

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Trending with Impact: Review of HER2 Variants in Breast Cancer Tumors

января 21, 2021

This review compiles splice variations in HER2 breast cancer, specifically in the context of the tumor environment, and co-expression of variants. The study also provides an up-to-date (as of Nov. 2020) account of HER2 and HER2 variant patterns of resistance to anti-HER2 therapies and other interventions. Oncotarget’s The Trending with Impact series highlights Oncotarget publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels. Look for future science news and articles about the latest trending publications here, and at Oncotarget.com. — Listen to an audio version of this article According to Cancer Research UK, breast cancer occurs in one in every eight women within their lifetime and is the second highest cause of cancer related deaths in the UK. Breast cancer is a blanketed term for a wide variety of tumors that occur in the mammary glands. In over 20% of breast cancers, the human epiderma

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